AnyVLM 1.0.0rc2.dev33+gb46b7e297

AnyVLM is an off-the-shelf solution for adding local aggregate-level variant information to a Variant-Level Matching (VLM) network. It provides a REST API service that integrates with GA4GH standards for genomic data exchange.

AnyVLM enables genomic research organizations to:

• Ingest VCF files containing variant and allele frequency data

• Register variants using the GA4GH Variant Representation Specification (VRS) via AnyVar

• Store cohort allele frequencies (CAF) with zygosity-stratified counts

• Serve VLM protocol-compliant responses with Beacon handover capabilities

This service is designed for rare disease variant frequency tracking in genomic research networks such as GREGoR.

If you’re setting up AnyVLM for the first time, begin with the Getting Started guide, which covers different installation options. To learn how to use AnyVLM as a service, see Usage. For further assistance, please refer to Getting Help.